产品货号：
Z29166
中文名称：
TrkC/NTRK3抗体
英文名称：
Anti-TrkC/NTRK3 Antibody
产品规格：
100μg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-TrkC/NTRK3 Antibody |
| 指标别名 | GP145 TrkC;gp145(trkC);NT 3 growth factor receptor;NTRK3;TrkC;TrkC tyrosine kinase |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | ELISA,IP,WB |
| 基因名称 | NTRK3 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids near the carboxyl terminus of mouse TrkCT1 protein. |
| 计算分子量 | 94kDa |
| 成分 | 0.02M Potassium Phosphate,0.15M Sodium Chloride,pH7.2,0.01% (w/v) Sodium Azide |
| 纯化方式 | This affinity purified antibody is directed against mouse TrkCT1 protein.The product was affinity purified from monospecific antiserum by immunoaffinity chromatography.?A BLAST analysis was used to suggest cross-reactivity with TrkCT1 protein from human,mouse and rat based on 100% homology with the immunizing sequence.Reactivity against homologues from other sources is not known. |
| 浓度 | 1.0mg/mL by UV absorbance at 280nm |
| 产品形态 | 溶液 |
| 保存条件 | Store vial at -20℃ prior to opening.Aliquot contents and freeze at -20℃ or below for extended storage.Avoid cycles of freezing and thawing.Centrifuge product if not completely clear after standing at room temperature.This product is stable for several weeks at 4℃ as an undiluted liquid.Dilute only prior to immediate use.Expiration date is one (1) year from date of opening. |
| 背景资料 | This antibody is suitable for Cancer,Immunology and Nuclear Signaling research.TrkCT1,also named neurotrophic tyrosine kinase receptor type 3 (Ntrk3) non-catalytic isoform 2,is a non-catalytic isoform of TrkC,the high affinity receptor for Neurotrophin-3 (NT-3).This isoform lacks the kinase domain that is responsible for signaling by the full-length isoform.?TrkCT1 is the product of an alternative splicing of Ntrk3 that leaves the extracellular and transmembrane domains intact but includes a shorter intracellular domain encoded by exons 13b and 14b.Recent studies indicate that the short cytoplasmic tail binds the scaffold protein Tamalin in a ligand-dependent manner and further activates the Arf6每Rac1 signaling pathway.Isoform 3 transcripts are readily detected early during embryogenesis and are expressed predominantly in adult brain and gonads. |
| Uniprot ID | Q6VNS1 |
| 基因名全称 | NT-3 growth factor receptor |
| 推荐稀释比 | ELISA:1:5,000 - 1:20,000 IP:1μg WB:1:1,000 - 1:10,000 |
相关搜索：TrkC/NTRK3抗体，TrkC抗体，NTRK3多抗，Anti-TrkC/NTRK3 Antibody